CLINICO-PATHOLOGICAL SPECTRUM OF ORAL CAVITY LESIONS WITH THEIR RADIOLOGICAL, HISTOPATHOLOGICAL & IMMUNOHISTOCHEMISTRY CORRELATION AT A TERTIARY CARE TEACHING HOSPITAL: A STUDY OF 200 CASES

  • Dr. Pragnanjalee Pravinbhai Domadiya,  
  • Dr. Neeru Dave,  
  • Dr. Darshan D. Dave,  
  • Dr. Vibhooti Manchhubhai Dhum*

Abstract

Background Oral cavity is the most vulnerable site for the different chemical injury, infection and trauma which further lead to development of the different lesions from non-neoplastic to neoplastic. Squamous cell carcinoma (SCC) is the most common malignancy. Most common site for SCC is buccal mucosa followed by tongue. Hence, Oral cancer is major health problem in developing countries due to habit of tobacco consumption. Clinico-pathological and radiological correlation is very helpful to diagnose these lesions in early stages for better management. Aims and objectives. This study is to analyse the radiological and pathological aspect of the oral cavity lesions with their spectrum in tertiary care teaching hospital. Materials and Methods A retrospective and prospective study of 200 cases was done in period of one and half year. The parameters included in the study were age, gender, site of the lesion and histopathological diagnosis. IHC markers were applied as per requirement. Collected data were analysed. Results Out of 200 cases, the age ranged from 4 to 80 years. Males were affected more often than females with a Male: Female ratio of 2.27:1. Malignant lesions were common than benign. Buccal mucosa was one of the most common site for SCC associated with the tobacco consumption. Conclusions: Oral cancer can be prevented and cured if detected early & hence further complications can be prevented.


Keywords

Keywords: oral cavity lesions, buccal mucosa, squamous cell carcinoma, tobacco consumption.